Horn SD. The Clinical Practice Improvement (CPI) Model and How It Is Used to Examine the Availability of Pharmaceuticals and the Utilization of Ambulatory Healthcare Services in HMOs: Results from the Managed Care Outcomes Project (MCOP). PharmacoEconomics 10 (Supplement 2, 1996): 50-55.

Many American healthcare facilities have come to understand that quality controls cost. Clinical Practice Improvement (CPI) is a methodology that creates a clinical laboratory—built into the everyday practice setting—to find and test best practices. A CPI study is an analysis of the content and timing of individual steps in a medical care process aimed at producing better clinical outcomes for the least necessary cost over the continuum of a patient’s care. Statistical regression analyses are used to determine whether and how much a particular step actually improves medical outcomes. Systematic determination of individual process steps that improve medical outcomes is the best way to develop demonstrably better care and practice. Combining CPI methodology and a data monitor creates a dynamic environment in which all patient encounters potentially contribute to improving the process of care.

We describe a recent multi-site study: the Managed Care Outcomes Project (MCOP). The MCOP study design permits us to compare the effects of various pharmaceutical treatments on resource utilization in actual practice in managed-care organizations. The MCOP database is an important resource for developing information required to design systems-based disease management programs.